In dorsally recumbent anaesthetized horses, CPAP of 8 cmH 2O results in redistribution of ventilation towards the dependent lung regions, thereby improving ventilation-perfusion matching. No differences were found for any VCap parameters. Venous admixture was significantly correlated with DSS with the treatment time taken as covariate (p < 0.0001 r = 0.65). In CPAP, the CoV shifted to dependent parts of the lungs (p < 0.001) and DSSs were significantly smaller (p < 0.001), while no difference was seen in NSSs. Statistical analysis was performed using multivariate analysis of variance and Pearson correlation.ĭata from six horses were statistically analysed. Lung regions with little ventilation, centre of ventilation (CoV) and dead space variables, as well as venous admixture were calculated. Electrical impedance tomography (and volumetric capnography (VCap) measurements were performed every 30 minutes. Horses were anaesthetized twice with isoflurane in 50% oxygen and medetomidine as continuous infusion in dorsal recumbency, and administered in random order either CPAP (8 cmH 2O) or NO CPAP for 3 hours. Randomized, experimental, crossover study. The aim of this study was to evaluate the effect of continuous positive airway pressure (CPAP) on regional distribution of ventilation and dead space in anaesthetized horses.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |